diff --git a/processor/ethereum/router/contracts/IRouter.sol b/processor/ethereum/router/contracts/IRouter.sol
index 91bedac5..f3fab5d6 100644
--- a/processor/ethereum/router/contracts/IRouter.sol
+++ b/processor/ethereum/router/contracts/IRouter.sol
@@ -36,11 +36,15 @@ interface IRouterWithoutCollisions {
   error EscapeHatchInvoked();
   /// @notice The signature was invalid
   error InvalidSignature();
+
   /// @notice The amount specified didn't match `msg.value`
   error AmountMismatchesMsgValue();
   /// @notice The call to an ERC20's `transferFrom` failed
   error TransferFromFailed();
 
+  /// @notice `execute` was re-entered
+  error ReenteredExecute();
+
   /// @notice An invalid address to escape to was specified.
   error InvalidEscapeAddress();
   /// @notice Escaping when escape hatch wasn't invoked.
diff --git a/processor/ethereum/router/contracts/Router.sol b/processor/ethereum/router/contracts/Router.sol
index e8f54653..fbff77c9 100644
--- a/processor/ethereum/router/contracts/Router.sol
+++ b/processor/ethereum/router/contracts/Router.sol
@@ -25,6 +25,14 @@ import "IRouter.sol";
 /// @author Luke Parker <lukeparker@serai.exchange>
 /// @notice Intakes coins for the Serai network and handles relaying batches of transfers out
 contract Router is IRouterWithoutCollisions {
+  /// @dev The address in transient storage used for the reentrancy guard
+  bytes32 constant EXECUTE_REENTRANCY_GUARD_SLOT = bytes32(
+    /*
+      keccak256("ReentrancyGuard Router.execute") - 1
+    */
+    0xcf124a063de1614fedbd6b47187f98bf8873a1ae83da5c179a5881162f5b2401
+  );
+
   /**
    * @dev The next nonce used to determine the address of contracts deployed with CREATE. This is
    *   used to predict the addresses of deployed contracts ahead of time.
@@ -356,6 +364,25 @@ contract Router is IRouterWithoutCollisions {
   // Each individual call is explicitly metered to ensure there isn't a DoS here
   // slither-disable-next-line calls-loop
   function execute4DE42904() external {
+    /*
+      Prevent re-entrancy.
+
+      We emit a bitmask of which `OutInstruction`s succeeded. Doing that requires executing the
+      `OutInstruction`s, which may re-enter here. While our application of CEI with verifySignature
+      prevents replays, re-entrancy would allow out-of-order execution of batches (despite their
+      in-order start of execution) which isn't a headache worth dealing with.
+    */
+    bytes32 executeReentrancyGuardSlot = EXECUTE_REENTRANCY_GUARD_SLOT;
+    bytes32 priorEntered;
+    // slither-disable-next-line assembly
+    assembly {
+      priorEntered := tload(executeReentrancyGuardSlot)
+      tstore(executeReentrancyGuardSlot, 1)
+    }
+    if (priorEntered != bytes32(0)) {
+      revert ReenteredExecute();
+    }
+
     (uint256 nonceUsed, bytes memory args, bytes32 message) = verifySignature();
     (,, address coin, uint256 fee, IRouter.OutInstruction[] memory outs) =
       abi.decode(args, (bytes32, bytes32, address, uint256, IRouter.OutInstruction[]));
diff --git a/processor/ethereum/router/src/tests/mod.rs b/processor/ethereum/router/src/tests/mod.rs
index 78215d95..2da5422d 100644
--- a/processor/ethereum/router/src/tests/mod.rs
+++ b/processor/ethereum/router/src/tests/mod.rs
@@ -22,6 +22,18 @@ use ethereum_deployer::Deployer;
 
 use crate::{Coin, OutInstructions, Router};
 
+#[test]
+fn execute_reentrancy_guard() {
+  let hash = alloy_core::primitives::keccak256(b"ReentrancyGuard Router.execute");
+  assert_eq!(
+    alloy_core::primitives::hex::encode(
+      (U256::from_be_slice(hash.as_ref()) - U256::from(1u8)).to_be_bytes::<32>()
+    ),
+    // Constant from the Router contract
+    "cf124a063de1614fedbd6b47187f98bf8873a1ae83da5c179a5881162f5b2401",
+  );
+}
+
 #[test]
 fn selector_collisions() {
   assert_eq!(
@@ -32,6 +44,10 @@ fn selector_collisions() {
     crate::_irouter_abi::IRouter::updateSeraiKeyCall::SELECTOR,
     crate::_router_abi::Router::updateSeraiKey5A8542A2Call::SELECTOR
   );
+  assert_eq!(
+    crate::_irouter_abi::IRouter::escapeHatchCall::SELECTOR,
+    crate::_router_abi::Router::escapeHatchDCDD91CCCall::SELECTOR
+  );
 }
 
 pub(crate) fn test_key() -> (Scalar, PublicKey) {